Professor Room was a researcher at the National Alcohol Research Centre (Berkeley, California) from 1963 to 1991; he was appointed as the Scientific Director from 1977 to 1991.
He was later appointed as Vice-President for Research at the Addiction Research Foundation of Ontario, Canada, from 1991 to 1998.
In 1999 Professor Room was appointed professor and founding director of the Centre for Social Research on Alcohol and Drugs at Stockholm University.
In March, 2006, he became Professor of Alcohol Policy Research at the School of Population Health of the University of Melbourne and the Director of the Centre for Alcohol Policy Research (CAPR) at Turning Point Alcohol & Drug Centre.
Among Professor Room's many awards is, Jellinek Memorial Award for Alcohol Studies.